Arizona quarterback Drew Stanton will likely make his second start since 2010 in place of injured QB Carson Palmer, against a tough San Francisco defense.
The Seahawks host the Broncos in a rematch of last year’s Super Bowl.
Former Tennessee Titans kicker Rob Bironas was killed in an overnight car crash. Bironas was married to Terry Bradshaw’s daughter, Rachel.
The Detroit Lions defeated the Green Bay Packers 19-7 to gain an early lead in the NFC North.
The New York Giants got their first win of the season by handing the Houston Texans their first loss of the season.
Playing without suspended-quarterback Jameis Winston, No. 1 Florida State defeated No. 22 Clemson 23-17 in overtime.
Mississippi State went into Death Valley and stunned No. 8 LSU 34-29.
No. 20 Kansas State looks to upset No. 5 Auburn in Manhattan.
The Jets appeared to tie the game against Green Bay, but offensive coordinator Marty Mornhinweg called a timeout right before the play. Watch here.