College Football Picks & Odds: Top 5 Best Bets Against the Spread Week 9

No. 3 Clemson -4.5 Over Florida State


Spread: Clemson by 4.5


Last Week: Both Teams Had a Bye Week


Why Clemson Covers: Both teams are coming off a bye and have had two weeks to prepare for this big matchup. Clemson is the better team and the metrics back this up. While the Tigers have struggled against average teams, they have played their best football against the top teams on their schedule. Clemson is ranked 4th in the S&P+ rankings while Florida State is ranked 14th. The OddsShark computer projects a 39.4-30.2 Clemson victory over Florida State. Look for Clemson to pull away in the fourth quarter on Saturday night. (Getty)