San Diego Chargers
Opponent: vs. Tennessee Titans
Line: SD (-5)
The Chargers are 3-5, but their biggest margin of defeat has been eight points, which came at Denver--one of the most difficult places to play against one of the best teams in the NFL--last week. Even with all the key players they've lost to injuries, they are one of just two teams in the league (Green Bay being the other) to rank in the Top 10 in both offensive and defensive efficiency, per Football Outsiders. Marcus Mariota is red-hot and the Titans have won three of their past four, but San Diego--outside of one ugly five-minute stretch against the Saints--has been excellent at home this year and should control this matchup. (Getty)