Henrikh Mkhitaryan could make his Premier League debut for United when they host West Ham.
Barcelona can clinch a place in the next round of Champions League when they visit Celtic Park.
Barcelona are back in Champions League action when they visit Celtic.
It’s winner-take-all in Group A, when PSG visit Arsenal for the top spot.
Paris Saint-Germain make a visit to North London, with the winner locking up a place in the knockout round.
Manchester United look to get back in the title race in an important match against Arsenal.
Arsenal look to keep their unbeaten streak alive when they make their annual visit to Old Trafford.
USMNT look to avoid an early 0-2 hole in World Cup qualifying when they visit Costa Rica.
Mexico can take control of first place in CONCACAF qualifying with three points against a resilient Panama squad.
After a disappointing loss to Mexico, USMNT visit Costa Rica, where they have lost eight straight qualifying visits.
Mexico look to win in Panama for the first time in 16 years when the teams meet Tuesday night.
USA head into hostile territory Tuesday night to face Costa Rica.
Argentina are in must-win mode when they host James Rodriguez and Colombia.
Chile look for a big home win when they host Suarez and Uruguay.
USA and Mexico renew their soccer rivalry when Mexico look to win their first game in Columbus in their last five attempts.