College Football Point Spreads & Odds Week 10

Unless you live in the Sooner State or are an alum of one of the schools, it’s probably not realistic to claim that Oklahoma-Oklahoma State is the best rivalry in college football. But their matchup has probably the best rivalry name in the sport: Bedlam. The No. 5 Sooners visit the No. 11 Cowboys (all rankings from new CFP Top 25) on Saturday in a crucial matchup, with OSU as a 3-point favorite on the Week 10 college football odds.

Bedlam is a potential eliminator game in three parts: for the Big 12 title, a spot in the College Football Playoff and the Heisman Trophy race. Oklahoma-Oklahoma State has decided the Big 12 title in four of the last six years. Because the conference brought back a Big 12 Championship Game this year, it moved the Bedlam game from the end of the regular season to November so there wasn’t a potential immediate rematch in that title game.

Both teams have one defeat overall (in conference) so the loser Saturday is out of the playoff, will find it extremely tough to get to the Big 12 title game, and the losing QB between the Sooners’ Baker Mayfield and Pokes’ Mason Rudolph has his Heisman hopes vanish (Rudolph is a longer shot as it is).

The road team has covered in four of the past five OU-OSU games, which is one of a handful of Top-25 showdowns on perhaps the best Saturday of the college football regular season.

In the SEC, No. 19 LSU visits No. 2 Alabama, which is a 21-point favorite. One reason why LSU fired Coach Les Miles last season was his inability to beat the Tide any longer. Bama has won the past six in the series, including 10-0 last year against current Tigers coach Ed Orgeron. LSU hasn’t been this big of an underdog against anyone since +27 against Florida in 1994.

No. 13 Virginia Tech visits No. 10 Miami, with the Hurricanes as 2.5-point underdogs despite joining Alabama, Georgia, Central Florida and Wisconsin as the country’s only unbeaten teams. The winner Saturday likely represents the Coastal Division in the ACC title game. Miami has yet to ever play in that game and has covered only two of its past eight at home in this series.

No. 22 Arizona is in Los Angeles to face No. 17 USC late Saturday night, with the Trojans as 7.5-point favorites. The winner there controls its destiny to play in the Pac-12 Championship Game.

The Wildcats have a rising superstar in QB Khalil Tate. He took over as the starter four games ago, and the Cats are 4-0 while averaging 48.8 points per game in them. Tate’s 840 rushing yards were the most by any player in an October in the past decade, and the sophomore won the Pac-12 Offensive Player of the Week award in all four weeks. The underdog has covered 10 of the past 12 in this series.

For more info, picks and a breakdown of this week’s top sports betting news check out the new OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes, or check it out at

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