DraftKings NFL Week 2 Fantasy: 5 Top Optimal Lineups & Picks

DraftKings Top Optimal Lineup

– QB: Tyrod Taylor vs. Saints ($5,900)

– RB: Alvin Kamara vs. Browns ($9,500)

– RB: James Conner vs. Chiefs ($6,700)

– WR: Jarvis Landry vs. Saints ($6,300)

– WR: Kenny Golladay vs. 49ers ($4,800)

– WR: Quincy Enunwa vs. Dolphins ($4,700)

– TE: George Kittle vs. Lions ($3,800)

– FLEX: Tevin Coleman vs. Panthers ($5,300)

– DST: Vikings ($2,600)

It goes without saying that the use of the Minnesota Vikings defense largely comes down to the status of Green Bay Packers quarterback Aaron Rodgers, who's currently listed as questionable. If Rodgers does play I'd likely shift my defense to either the San Francisco 49ers ($2,800) or Atlanta Falcons ($2,700).

Going beyond that, there's a bit of a trend that's likely pretty obvious here. The first is that I want the high upside pairing of Tyrod Taylor and Jarvis Landry against a New Orleans Saints defense that just got torched by Ryan Fitzpatrick and the Tampa Bay Buccaneers. I do expect the Saints to be somewhat better in Week 2, but they gave up 361 yards and four touchdowns to the wide receiver position last week, there's no way to overlook that.

One of my other areas of focus will be on a few players whose prices didn't adjust on DraftKings since they played in the Monday Night Football game. This includes (in my optimal lineup) wideouts Kenny Golladay and Quincy Enunwa.

To be clear, I don't expect either player to post quite the numbers they did last week, but both have fine matchups and low price tags, allowing me to get my high-dollar targets in. Golladay was an absolute monster in Week 1 against the New York Jets, receiving 12 targets and catching seven of them for 114 yards. While those numbers are unlikely to be an every-week occurrence, we could easily see Golladay haul in 4-5 passes and one or two touchdowns. At $4,800, I'll take that production every single week.

Enunwa is another name who surprised fantasy owners last week, and he's probably more of a "high floor" play, at least from what we saw in the opener. It was apparent Enunwa has taken on the role of rookie quarterback Sam Darnold's safety blanket, seeing a team-high 10 targets and finishing with six catches for 63 yards and one touchdown. Unfortunately, we don't know exactly what the Dolphins pass defense will look like this season, as they played a Tennessee Titans team which was led by Blaine Gabbert for much of the game.

I'll roll out the three running back set with a smile on my face this week, and it's largely due to a mixture of injuries (or holdouts) and matchups. I actually believe the Browns defense won't be bad this season, but the fact that they'll be playing a game in normal weather will force them to give Drew Brees plenty of attention. Even though the Browns were playing in 20-30 MPH winds last week, they allowed 135 rushing yards and two touchdowns to running backs in Week 1. For good measure, Cleveland also allowed backs to catch five passes for 57 yards. This all bodes well for Alvin Kamara, who has one of the safest workloads in the NFL.

As for James Conner and Tevin Coleman, we have two very different but nice situations working in our favor. Starting with Conner, who's holding down the fort for Le'Veon Bell, he impressed in the opener by posting all of the aforementioned numbers against the Browns. Conner has a huge workload and is priced just above a mid-range running back at $6,700. The Chiefs also allowed 14 receptions to running backs last weekend, so it's a safe bet we're going to see plenty of pass-catching work for Conner.

With the Atlanta Falcons ruling out Devonta Freeman, it's time for all the Coleman. The matchup against the Panthers isn't ideal, but based on pure workload and previous success without Freeman, I'm absolutely using the young back at this price. Here's a look at Coleman's numbers without Freeman last year alone.

– vs. Dallas Cowboys: 20 carries, 83 rushing yards, one touchdown
– at Seattle Seahawks: 20 carries, 43 rushing yards, one touchdown
– vs. Tampa Bay Buccaneers: 19 carries, 97 rushing yards, two touchdowns

Finally comes my $3,800 salary-saving tight end in George Kittle. The best part about Kittle is I actually believe he'll have low ownership to some extent. With Jared Cook cheaper ($3,600), the 49ers tight end could get overlooked. It's a good spot with Marquise Goodwin battling an injury and Jimmy Garoppolo still building rapport with Pierre Garcon. It wasn't noticed in a big way, but Kittle caught five passes for 90 yards last week and saw two red zone targets.

Let's move along to the high-upside lineup which features a few major boom-or-bust plays.