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NFL Week 16 Predictions: Best Picks Against the Spread

Only two weeks remain in the NFL regular season, and the playoff picture is about as clear as mud. A few teams have clinched playoff spots and division titles, but there are still first-round byes, home-field advantage, remaining divisional crowns and wild-card spots to be determined. Week 16 crosses over with Christmas, which falls on a Sunday this year, so the schedule will be a little different with one game on Thursday, 12 on Saturday, two on Sunday and one on Monday. Only five games aren't intra-division matchups, while six are between potential playoff teams, including both on Christmas (Baltimore at Pittsburgh, Denver at Kansas City) and the Monday night game (Detroit at Dallas). In other words, it's going to be a highly entertaining week of holiday football. You can click through the gallery for my favorite picks against the spread (odds courtesy of OddsShark) or you can read here for more picks and analysis. (Getty)

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NFL Week 16 odds, predictions and the best picks against the spread.