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FanDuel NFL Week 1 Lineup Picks, Advice & Analysis

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Gallery: 3/10

RB: Ryan Mathews, PHI (vs CLE), $6,100

New Eagles head coach Doug Pederson has always ran an offense that goes through the featured running buck, and that will especially be the case with rookie quarterback Carson Wentz under center. Mathews may cede third downs to Darren Sproles, but he's in line for a big workload at home against a Cleveland Browns run defense that is expected to be one of the worst units in the NFL this season. Yes, please. (Getty)

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With a handful of projected high-scoring Week 1 games, we take a closer look at the best picks for FanDuel DFS lineups.