Gallery: 2/6
Seattle Seahawks
Opponent: vs. Arizona Cardinals
Line: SEA (-8.5)
The Seahawks and Cardinals played to an ugly 6-6 tie back in October, but circumstances are different this time around. First, the game is in Seattle, where the 'Hawks are 7-0 and outscoring opponents 196-102, compared to the road where they are 2-4-1 and being outscored 102-133. Second, the Seahawks are battling for a first-round bye in the playoffs, while the Cardinals have only a draft pick to play for, so motivations will be far different on either side. This one has blowout written all over it. (Getty)
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NFL Week 16 Predictions: Best Picks Against the Spread