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NFL Week 16 Predictions: Best Picks Against the Spread

Denver Broncos


Opponent: at Kansas City Chiefs


Line: DEN (+4)


Kansas City's style of football just doesn't typically lend itself to a lot of big victories, as five of the Chiefs' last six games have been decided by three points or less. Throw in the fact that Denver's elite defense often keeps the Broncos close--they've lost by more than a touchdown just twice this season--and this one figures to be a tight one, just as it was last month when they went to overtime before the Chiefs ultimately won by a field goal. Although I think Kansas City ultimately wins this one at home, I like getting Denver plus four points in what is projected as the lowest scoring game of the week with an over/under of just 37.5. (Getty)

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NFL Week 16 odds, predictions and the best picks against the spread.