Dopamine and How it Affects Pleasure and Addiction

The Unyielding Power of DopamineNew videos DAILY: Join Big Think Edge for exclusive videos: ———————————————————————————- ———————————————————————————- ABOUT BIG THINK: Smarter Faster™ Big Think is the leading source of expert-driven, actionable, educational content — with thousands of videos, featuring experts ranging from Bill Clinton to Bill Nye, we help you get smarter, faster. S​ubscribe to learn from top…2012-04-24T01:07:41Z

Dopamine is one of the neurotransmitters in the brain, and it’s closely linked to pleasure. When dopamine is released in the brain, we feel happy. Dopamine gives us a feeling of well-being and euphoria. Because of this, it’s tied to depression, sex, drug and alcohol abuse, ADHD, and paranoia.

Watch the video above as drug addiction expert Nora Volkow, M.D., explains the link between dopamine and drug use. Dr. Volkow is the Director of the National Institute on Drug Abuse.

Why is dopamine such a powerful chemical?

Dopamine serves to send messages between cells in the brain. It enables a wide variety of functions, like movement. When your dopamine cells die, for example, you cannot initiate movement. That is Parkinson’s Disease.

It also modulates the areas of our brain that affect our ability to perceive reward and to be motivated into action. For example, in lab studies, genetically modified animals without dopamine will die of starvation because they don’t have motivation to find food and eat. That’s how important dopamine is- it gives you that energy and drive to do something.

Dopamine, Sex, and Pleasure

These mechanisms are not developed in our brains just to give us pleasure. Dopamine has an important role in nature, and it is to condition us (and animals) to perform behaviors that will insure our survival. That is why our dopamine levels rise when we eat or when we have sex.

Dopamine and Drug Addiction:

Drugs, whether legal or illegal, increase dopamine in certain areas of the brain. This ability to increase dopamine is directly associated with rewarding or reinforcing effects. But unlike our natural response to food and sex, dopamine levels do not decline with repeated drug use in some people. After you eat, your dopamine levels decrease. You are full. In people who are more vulnerable, they cannot control their ability to decide when to take their drug of choice. That’s addiction.

Risk Factors for Drug Addiction

1. Addiction has a strong genetic component. Scientists estimate that genes make up about half of a person’s vulnerability to become an addict, as people with low dopamine levels are more likely to become addicts.

2. The other important important vulnerability of addiction is age of exposure. If you are exposed to drugs as an adolescent, you are much more likely to become addicted than if you are exposed to the drugs as an adult.


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