United look to bounce back from a poor showing against Chelsea when they take on City in Cup action.
Chelsea host West Ham in midweek EFL Cup play.
Injuries on both sides could affect how Pep and Mourinho set their lineups for Wednesday’s derby.
United are a narrow favorite when they host rivals City in midweek League Cup action.
Jose Mourinho, twice manager of Chelsea, leads United into Stamford Bridge on Sunday to face his former club.
United play their third game in six days Sunday at Chelsea, who have won their last two league fixtures by a combined score of 5-0.
With some good fortune and a win over West Brom, Liverpool could end the day atop the Premier League table.
Barcelona can reclaim their space at the top of the Spanish table with a win over Valencia.
Arsenal host Middlesbrough on the 67th birthday of Arsenal manager Arsene Wenger.
United are back at Old Trafford to host Turkish side Fenerbahce in Europa League play.
Manchester City’s fate was sealed Wednesday when Claudio Bravo was sent off early in the second half.
Follow live as City attempt to become the first Premier League team to win at Camp Nou since 2007.
Bayern are looking for their first win in four matches when they host PSV.
Barcelona host Manchester City in the biggest matchup of Wednesday’s action.
Arsenal go for their seventh straight wins in all competitions when they host Bulgarian club Ludogorets.