USA and Cuba play a friendly in Havana for just the second time in history.
Argentina hit the road without the injured Messi to face Peru in a big World Cup qualifier.
Neymar and Brazil continue World Cup qualifying against Bolivia.
Uruguay hope to extend their lead at the top of the qualifying table by defeating Venezuela.
Juan Cuadrado and Colombia take on Paraguay, who are currently on the wrong side of CONMEBOL qualifying.
Ecuador look to continue their strong start to CONMEBOL qualifying when they host Chile.
Expect to see some of the world’s best on the field when Italy host Spain in World Cup qualifying.
Wales look to keep their impressive 2016 going with a win over Austria in World Cup qualifying.
World Cup qualifying pits two of the top national teams in Europe against each other when Spain take on Italy.
Manchester City look to contine their red-hot start to the season when they face Spurs.
United have a short turnaround after midweek Europa League action when they take on Stoke.
Costa and Chelsea visit Hull City, who have been outscored 9-2 in their previous two fixtures.
United welcome Ukranian League side Zorya Luhansk to Old Trafford for Europa League action.
Top teams from Spain and Germany collide in Champions League group play.
Pro Evolution Soccer 2017 does enough to keep its fanbase pleased with another round of top-notch soccer.