Tyquan Lewis: Everything you need to know

Lewis recorded 11 tackles (five solo) including 3.0 sacks and a pass defensed in 13 games with Indianapolis in 2025. Lewis' three prior years demonstrated that he's more efficient and durable as a pass rusher if he's only called to play a limited role, but the veteran ended up having to battle through groin and ankle injuries after he averaged 30.8 snaps per game over the first five contests of the campaign. He's currently on track to become a free agent during the offseason, and he could likely contribute for a team in need of depth on the edge in 2026.

Lewis (ankle) has been upgraded and carries no injury designation ahead of Sunday's matchup against the Seahawks. The 30-year-old practiced in full Friday, and despite his original questionable designation, he'll suit up for the Week 15 matchup. Lewis has underwhelmed through nine appearances this season, recording just eight total tackles, including 3.0 sacks, and one pass defensed. Now fully healthy, he's expected to operate as one of the Colts' top reserve defensive ends Sunday.

Lewis (ankle) is listed as questionable ahead of Sunday's game against the Seahawks. Lewis was absent for the Colts' Week 14 loss, but he progressively increased his practice involvement ahead of Sunday's game against Seattle. He upgraded to a full session Friday but will remain questionable for the time being.