When Can Children Get the COVID-19 Vaccine? 5 Questions Answered

Getty Erin Lilly becomes the first person in Cornwall to receive their Covid-19 vaccination as the Royal Cornwall Hospital began their vaccination program on December 9, 2020 in Truro, United Kingdom.

The first U.S. COVID-19 vaccines are expected in clinics in mid-December, and states are drawing up plans for who should get vaccinated first.

But one important group is absent: children.

While two vaccines are expected to be cleared soon for adult use in the U.S., testing is only now getting started with children – and only with adolescents. There are still a lot of unknowns.

As an infectious disease pharmacist and professor who helps manage patients hospitalized with COVID-19, I frequently hear questions about vaccines. Here’s what we know and don’t know in response to some common questions about vaccinating kids for COVID-19.

1. When Can My Child Be Vaccinated?


NIAID, CC BYThe coronavirus gets its name from the spike proteins that ring it like a corona, visible here under an electron microscope. The Pfizer and Moderna vaccines target these proteins.

Right now, it appears unlikely that a vaccine will be ready for children before the start of the next school year in August.

Adult trials of the two leading vaccines have had promising results. A Food and Drug Administration briefing paper released on Dec. 8 indicated the vaccine made by Pfizer appeared to meet U.S. standards for emergency use authorization for adults, suggesting it was on the cusp of approval. The British government has already approved the vaccine and started vaccinating adults in the U.K.

But clinical trials involving children are only just getting started.

Pfizer, working with Germany’s BioNTech, expanded its COVID-19 vaccine testing to children ages 12 and older only in October. The other leading vaccine maker, Moderna, announced on Dec. 2 that it planned to begin COVID-19 vaccine trials in children ages 12-17 soon.

The vaccine’s efficacy and safety will have to be evaluated for each age group, and testing hasn’t started for infants, toddlers or kids in the U.S.

Clinical trials are designed to ensure that the vaccine is safe and effective. Typically, it takes 10 to 15 years from the start of development until the vaccine is licensed, but the COVID-19 vaccines are being developed faster in response to the pandemic.

2. Will Children Need More Shots Than Adults?

children covid19 vaccine

@VI4research, CC BY-NC-SAVaccines help the immune system recognize viruses, typically by injecting weakened virus or the virus’s proteins. Pfizer and Moderna developed a new type of vaccine that instead uses mRNA, the molecular instructions for building virus proteins

It does not appear that the schedule of COVID-19 vaccine doses will be different for children, but that could change as testing goes on.

Pfizer’s vaccine is being tested in adolescents with a two-dose series, three weeks apart, just like in adults. Moderna also plans to use its adult schedule – two doses four weeks apart – in an upcoming trial with 3,000 adolescents.

The second dose serves as a “booster shot,” since the first dose alone doesn’t provide optimal immunity. This is consistent with several other vaccines, including hepatitis B, measles, mumps and rubella.

Right now, only those two doses are planned, but that could change. It’s unclear how long the immune response from these COVID-19 vaccines will last or if more doses will be necessary in the future. The flu vaccine, for example, requires a new dose every year because the virus changes. Recent promising data from Moderna indicate immunity is sustained for at least three months after receiving the COVID-19 vaccine.

3. Are the Vaccines Safe for Kids?

coronavirus vaccine

GettyAn illustration picture shows vials with Covid-19 Vaccine stickers attached and syringes with the logo of US pharmaceutical company Pfizer, on November 17, 2020.

So far, no serious safety concerns have been identified with either the Pfizer or Moderna vaccines, but the trials are still in the early stages for children. Several other vaccines are also under development around the world, and a few drugmakers have started trials with younger children in other countries.

Another concern people raise is about temporary side effects.

Children tend to have stronger immune systems than adults, and they may have stronger temporary reactions to the vaccine. That could mean more pain and swelling at the injection site for a few days and possibly a fever.

These side effects are common with vaccines. They’re evidence that the immune system is doing what it should be doing, but they can be scary.

Both the safety of the vaccine and the likelihood of temporary side effects are important to understand, because adults and children will need both doses for the vaccine to provide optimal immunity.

4. Is Vaccinating Adults Enough?

pink eye coronavirus

GettyA researcher works on a vaccine against the new coronavirus COVID-19 at the Copenhagen’s University research lab in Copenhagen, Denmark, on March 23, 2020

Just vaccinating adults would not be enough to end the pandemic. Children can still become infected, transmit the virus and develop complications. If a vaccine is not available, children will likely serve as a reservoir of the virus, making it harder to end the pandemic.

Both leading vaccines have reported promising results in adults so far: The efficacy rate is approximately 94% for Moderna’s vaccine and 95% for Pfizer’s. That means that under the best conditions, about 95% percent of adults who get the vaccine have been found to be protected. That’s higher than expected.

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Whether the same holds for children remains to be seen.

Children typically have milder COVID-19 symptoms than adults, but they can still transmit the virus to others.

Receiving the vaccine also carries other benefits, including allowing a safer return to schools and activities.

Do We Have to Keep Wearing Masks & Social Distancing?

santa covid

GettySanta chats with a visiting child on December 6, 2020 in Seattle, Washington.

In the meantime, it will be important to continue standard preventive measures, including social distancing, wearing face masks, washing hands and following other guidance from the Centers for Disease Control and Prevention.

While the hope is that a vaccine will allow people to get back to a more “normal” way of living, these preventive measures will still be needed, even after receiving the vaccine, until more information is known about the extent of protection from the vaccine.

There are still many unanswered questions. As time goes on, we’ll have more answers.The Conversation

By Wesley Kufel, Clinical Assistant Professor, Pharmacy Practice, Binghamton University, State University of New York

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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