De Los Santos gave up a hit and a walk over 1.1 scoreless innings Wednesday to record his third save of the season in a 2-0 win over the Guardians. He struck out one. The journeyman righty wrapped up the combined shutout on 24 pitches (16 strikes), although De Los Santos did make things interesting by putting the tying runner on base in the ninth inning with two outs. He's converted three straight save chances since April 14, emerging as the preferred closing option for manager Joe Espada while the Astros continue to navigate the absence of Josh Hader (bicep), but De Los Santos' 3.86 ERA, 1.18 WHIP and 8:3 K:BB through 9.1 innings this season don't suggest he'll have a long-term spot in the team's high-leverage crew.
Enyel De Los Santos: Everything you need to know
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Status
ACTIVESTATS
Enyel De Los Santos Game Log 2026
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Regular SeasonDateOppResultIPKBBHBPCGSHOHRER5/6L 12-21.0000000005/3W 3-11.0100001005/2W 6-31.2100001114/30W 11-51.0210001004/26W 7-41.0000004334/22W 2-01.1110001004/21L 8-50.1010002334/19L 7-51.0100001004/15W 3-11.0200000004/14W 7-60.1100000004/12L 6-11.1000000004/10L 9-61.0100001004/8L 9-12.0210002114/6L 9-71.000000100
Regular Season Totals 13.61240001588
Enyel De Los Santos Splits 2026
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SplitsGSIPWLERAKBBHBPCGHRERSVOSAVGHR
Overall 015.0010.0124001588330.2501Away 010.2010.084001055110.2381Home 04.1000.04000533220.2780Night 03.2010.04100433220.2670Day 011.1000.083001155110.2441vs Lefty 00.0000.04200960000.2500vs Righty 00.0000.08200620000.2501April 011.1010.0104001377330.2771May 03.2000.02000211000.1540Opponent vs BOS 0 2.2 0 0 0.0 2 0 0 0 2 1 1 0 0 0.200 0 vs CLE 0 1.2 0 1 0.0 1 2 0 0 3 3 3 1 1 0.375 0 vs COL 0 4.1 0 0 0.0 5 1 0 0 3 1 1 2 2 0.188 1 vs STL 0 1.0 0 0 0.0 1 0 0 0 1 0 0 0 0 0.250 0 vs NYY 0 1.0 0 0 0.0 0 0 0 0 4 3 3 0 0 0.571 0 vs BAL 0 1.0 0 0 0.0 2 1 0 0 1 0 0 0 0 0.250 0 vs SEA 0 2.1 0 0 0.0 1 0 0 0 1 0 0 0 0 0.125 0 vs LAD 0 1.0 0 0 0.0 0 0 0 0 0 0 0 0 0 0.000 0 Venue @ Seattle 0 2.1 0 0 0.0 1 0 0 0 1 0 0 0 0 0.125 0 @ Baltimore 0 1.0 0 0 0.0 2 1 0 0 1 0 0 0 0 0.250 0 @ Boston 0 2.2 0 0 0.0 2 0 0 0 2 1 1 0 0 0.200 0 @ Cleveland 0 1.2 0 1 0.0 1 2 0 0 3 3 3 1 1 0.375 0 @ Colorado 0 3.0 0 0 0.0 2 1 0 0 3 1 1 0 0 0.250 1 @ Houston 0 4.1 0 0 0.0 4 0 0 0 5 3 3 2 2 0.278 0
Enyel De Los Santos Player Profile
Career History
Enyel De Los Santos: Breaking News
Stuck with loss
De Los Santos (0-1) took the loss Tuesday against the Guardians, allowing three runs on two hits and a walk in one-third of an inning. Tasked with protecting a two-run lead in the eighth inning, De Los Santos allowed three of the four batters he faced to reach safely, opening the door for Cleveland's six-run frame. Prior to Tuesday, De Los Santos had given up just one run across 7.2 innings in his first seven appearances this season while seeing closing opportunities in the absence of Josh Hader (biceps).
Another save for Houston
De Los Santos earned the save with a perfect ninth inning in a 3-1 victory over the Rockies on Wednesday. He struck out two. The 30-year-old right-hander has now earned saves on consecutive days for Houston, career saves No. 4 and 5, as De Los Santos appears to be entering the closer mix in the absence of Josh Hader (biceps) and in light of Bryan Abreu's struggles this season. Abreu pitched 1.1 scoreless innings in Wednesday's victory, setting up the save chance for De Los Santos after Bryan King did as much Tuesday. De Los Santos' fastball velocity is down a couple ticks to around 94 mph this season, but it seems to be by design since he's cut his walk rate by more than half in the early going, an improvement that has helped fuel a 1.35 ERA and 0.75 WHIP through six appearances and 6.2 innings so far in 2026.